Table of Contents
Definition / general | Case reports | Gross description | Microscopic (histologic) description | Positive stains | Negative stainsCite this page: Ehdaivand S. Primary retroperitoneal mucinous cystadenoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ovarytumorprimaryretromuccystadeno.html. Accessed June 5th, 2023.
Definition / general
- Uncommon, found only in women
- Resembles ovarian mucinous cystadenoma but is not attached to ovary
- Appears to arise from mesothelial cell inclusions and subsequent mucinous metaplasia to form a cystadenoma
Case reports
- 25 year old woman with 30 cm retroperitoneal cystic mass (Arch Pathol Lab Med 2001;125:691)
Gross description
- Thin walled (1 mm) multilocular cyst containing clear serous fluid; smooth inner lining
Microscopic (histologic) description
- Lining composed of tall columnar cells with clear cytoplasm and basal nuclei; also low cuboidal cell resembling mesothelial cells
- Stroma is densely cellular and collagenous with closely packed spindle cells
Positive stains
- PAS / diastase and Alcian blue (pH 2.5) in tall columnar cells
- ER in stroma and low cuboidal cells
- Calretinin in low cuboidal cells
- Both cell types positive for CAM 5.2, CK7, CK20
Negative stains
- PAS / diastase and Alcian blue (pH 2.5) in low cuboidal cells
- ER and calretinin negative in tall columnar cells
- All cells negative for B72.3, PR, CEA
