Mucinous tumors

Primary retroperitoneal mucinous cystadenoma

Last author update: 1 July 2012
Last staff update: 19 October 2020

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PubMed search: Primary retroperitoneal mucinous cystadenoma

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Cite this page: Ehdaivand S. Primary retroperitoneal mucinous cystadenoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ovarytumorprimaryretromuccystadeno.html. Accessed June 5th, 2023.
Definition / general
  • Uncommon, found only in women
  • Resembles ovarian mucinous cystadenoma but is not attached to ovary
  • Appears to arise from mesothelial cell inclusions and subsequent mucinous metaplasia to form a cystadenoma
Case reports
Gross description
  • Thin walled (1 mm) multilocular cyst containing clear serous fluid; smooth inner lining
Microscopic (histologic) description
  • Lining composed of tall columnar cells with clear cytoplasm and basal nuclei; also low cuboidal cell resembling mesothelial cells
  • Stroma is densely cellular and collagenous with closely packed spindle cells
Positive stains
  • PAS / diastase and Alcian blue (pH 2.5) in tall columnar cells
  • ER in stroma and low cuboidal cells
  • Calretinin in low cuboidal cells
  • Both cell types positive for CAM 5.2, CK7, CK20
Negative stains
  • PAS / diastase and Alcian blue (pH 2.5) in low cuboidal cells
  • ER and calretinin negative in tall columnar cells
  • All cells negative for B72.3, PR, CEA
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