Other tumors

Sebaceous adenoma

Topic Completed: 1 March 2015

Minor changes: 22 October 2020

Copyright: 2002-2021, PathologyOutlines.com, Inc.

PubMed Search: Sebaceous adenoma [title]

Nalini Gupta, M.D.
Page views in 2020: 1,142
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Cite this page: Gupta N. Sebaceous adenoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/ovarytumorsebaceousadenoma.html. Accessed October 21st, 2021.
Definition / general
  • Benign sebaceous tumor, usually on head and neck (Pathology 1987;19:204), often associated with Muir-Torre syndrome
  • Single case is reported in ovary arising within an ovarian mature cystic teratoma in a patient with Muir-Torre syndrome (Ann Diagn Pathol 2012;16:485), an autosomal dominant disorder characterized by neoplasms of skin (sebaceous adenoma, sebaceous epithelioma, sebaceous carcinoma or keratoacanthoma) and a GI / GU / gyn malignancy (eMedicine)
Prognostic factors
  • Complete excision is curative
Microscopic (histologic) description
  • Incompletely differentiated sebaceous lobules, irregular in size and shape
  • Undifferentiated basaloid cells peripherally and mature sebaceous cells centrally
Microscopic (histologic) images

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Positive stains
Negative stains
Differential diagnosis
  • Sebaceous hyperplasia: < 5 mm; associated with hair follicles
  • Sebaceoma: basaloid cells predominate over mature sebocytes
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