Herpes simplex pancreatitis

Topic Completed: 1 August 2012

Minor changes: 6 March 2020

Copyright: 2002-2020,, Inc.

PubMed Search: Herpes simplex[TIAB] pancreatitis[TIAB]

Deepali Jain, M.D.
Page views in 2019: 93
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Cite this page: Jain D. Herpes simplex pancreatitis. website. Accessed August 6th, 2020.
Definition / general
Gross description
  • Small, discrete foci of hemorrhagic necrosis
Microscopic (histologic) description
  • Parenchymal necrosis, hemorrhage, minimal fat necrosis, mild neutrophilic infiltrate compared to intensity of necrosis (Arch Pathol Lab Med 2003;127:231)
  • Atrophic acinar cells
  • Numerous eosinophilic intranuclear inclusions with clear halos (Cowdry type A), many multinucleated giant cells with hyperchromatic irregular nuclei and eosinophilic cytoplasm
  • Some nuclei have basophilic, ground glass / smudged appearance
Microscopic (histologic) images

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