Grossing, features to report & frozen section

Topic Completed: 1 August 2012

Minor changes: 18 November 2021

Copyright: 2002-2022,, Inc.

PubMed Search: Features to report[TIAB] pancreas

Deepali Jain, M.D.
Page views in 2021: 1,032
Page views in 2022 to date: 45
Cite this page: Jain D. Grossing, features to report & frozen section. website. Accessed January 17th, 2022.
Features to report (includes endocrine tumors)
  • Tumor size
  • Tumor location
  • Histopathologic type
  • Histologic grade (well, moderate, poor or undifferentiated; not necessary for endocrine tumors)
  • Perineurial invasion
  • Angiolymphatic invasion
  • Margins (common bile duct, pancreatic duct, retroperitoneal margin [soft tissue adjacent to superior mesenteric artery], surgical margin)
  • Endocrine tumors: mitotic activity, necrosis, pleomorphism, amyloid
  • Involvement of adjacent structures
  • Lymph nodes
  • Presence of PanIN (including marginal involvement)
  • Findings in remaining pancreas (pancreatitis, nesidioblastosis for endocrine tumors)

  • References: Arch Pathol Lab Med 2000;124:30 (endocrine tumors)
Diagrams / tables

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Pancreas and duodenum


Grossing of Whipple specimen

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