Microbiology & parasitology

Parasites-gastrointestinal (not liver)

Iodamoeba bütschlii

Topic Completed: 1 October 2018

Minor changes: 5 October 2020

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PubMed Search: Iodamoeba bütschlii

Nat Pernick, M.D.
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Cite this page: Pernick N. Iodamoeba bütschlii. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/parasitologyiodamoebabutschlii.html. Accessed October 15th, 2021.
Definition / general
  • Nonpathogenic ameba that can colonize the large intestine
  • The name Iodamoeba comes from the large clear space in the cytoplasm
  • Acquired by ingesting contaminated food or water
  • Does not appear to be associated with HIV infection
Case reports
Cytology description
Cytology images

Contributed by Bobbi Pritt, M.D.

Anal Pap smear

Case #402

Anal Pap smear

Differential diagnosis
  • Entamoeba histolytica: similar size but its cytoplasm often contains ingested red blood cells and its nucleus has a smaller karyosome with a peripheral rim of condensed chromatin
  • Endolimax nana and other nonpathogenic amebae: may be difficult to differentiate from I. bütschlii; requires a stool examination in the microbiology lab; nonpathogenic amebae can travel with pathogenic organisms (Diagn Cytopathol 2014;42:775)
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