Penis & scrotum
General
Grossing-penectomy
Authors: Shaheed W. Hakim, M.D., Trevor A. Flood, M.D.
Topic Completed: 1 June 2014
Minor changes: 1 July 2020
Copyright: 2002-2019, PathologyOutlines.com, Inc.
PubMed Search: Gross penectomy
Cite this page: Hakim SW, Flood TA. Grossing-penectomy. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/penscrotumgrossingpenect.html. Accessed August 6th, 2020.
Procedure
- In the fresh state, cut the proximal resection margin en face
- Three important areas of the resection margin need to sampled:
- Proximal urethra and surrounding periurethral cylinder composed of epithelium, subepithelial connective tissue (lamina propria), corpus spongiosum and penile fascia
- The urethra may be retracted but it is important to locate it and submit its circumference entirely
- Corpora cavernosa separated and surrounded by tunica albuginea and Buck fascia
- Skin of shaft with underlying corporal dartos
- Proximal urethra and surrounding periurethral cylinder composed of epithelium, subepithelial connective tissue (lamina propria), corpus spongiosum and penile fascia
- Fix the remaining specimen in 10% buffered formalin overnight
- After fixation, section the glans and shaft longitudinally (sagitally) in two halves, using the meatus and anterior urethra as a guide
- Do NOT probe the urethra as doing so can result in distortion of the urethral mucosa
- If foreskin is present:
- Measure its length and identify the presence / absence of phimosis
- If not affected by tumor, separate the foreskin leaving a 3 mm margin from the coronal sulcus and include it as a circumcision specimen
- Do NOT remove foreskin if it is affected by tumor
- Document the tumor size, location, color, growth pattern and distance from resection margin
- Take a photograph of the specimen showing the maximum tumor depth of invasion
- Map the photograph according to sections submitted
- Section each half longitudinally along the specimens' longest axis, at 3 to 5 mm intervals
- Submit entirely the section which depicts the deepest anatomical level infiltrated by tumor
- If tumor affects multiple anatomical compartments, submit at least three sections of each compartment affected
- Sections should always attempt to include adjacent nontumoral mucosa
Diagrams / tables
AFIP images
Periurethral corpus spongiosum involvement
Images hosted on other servers:
Cross section of the penis
Penis anatomy
Gross images
AFIP images
SCC involves corpora cavernosa
Partial penectomy specimen
Images hosted on other servers:
Mapped partial penectomy specimen
Additional references
