Penis & scrotum

Male urethra

Benign male urethral lesions



Last author update: 1 June 2012
Last staff update: 23 July 2021

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PubMed Search: urethra benign lesions male

Turki Al-Hussain, M.D.
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Cite this page: Al-Hussain T. Benign male urethral lesions. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/prostatebenignmaleurethralesions.html. Accessed November 29th, 2023.
Diverticula

Definition / general:
  • Usually women, either acquired or congenital
  • In adults, usually secondary to infection, trauma, calculus, obstruction, dilation or inflammation of paraurethral gland
  • Carcinoma may arise in diverticula very rarely


Microscopic (histologic) description:
  • Lined by urothelium, with or without squamous or glandular metaplasia
  • Submucosa is often edematous and inflamed
  • Nephrogenic adenoma may arise in diverticula
Inverted papilloma

Definition / general:
  • Rare in urethra
  • Similar to those in bladder
Leiomyoma

Definition / general:
  • Most common soft tissue tumor of urethra
  • Relatively common in women, rare (< 10 reported) in men


Case report:
  • 48 year old man with quadriplegia (Arch Pathol Lab Med 2000;124:302)
  • Nephrogenic (mesonephric) adenoma

    Definition / general:
    • Metaplastic change, not neoplastic, common in urethra
    • Similar to lesions in bladder neck
    Papilloma

    Definition / general:
    • Rare in urethra
    • Similar to those in bladder
    Polypoid urethritis

    Definition / general:
    • Urethral counterpart of polypoid cystitis
    Prolapse

    Definition / general:
    • May occur in childhood and simulate a neoplasm
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