Prostate gland & seminal vesicles
Mesenchymal tumors
Leiomyoma
Author: Komal Arora, M.D.
Last author update: 1 June 2012
Last staff update: 20 January 2022
Copyright: 2003-2023, PathologyOutlines.com, Inc.
PubMed search: Prostatic leiomyoma
Table of Contents
Definition / general | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Differential diagnosisCite this page: Arora K. Leiomyoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/prostateleiomyoma.html. Accessed September 30th, 2023.
Definition / general
- Rare; glandular hyperplasia with small areas of leiomyomatous growth is more common (Arch Esp Urol 2011;64:631)
Microscopic (histologic) description
- Well organized fascicles of spindle cells
- Normocellular; no / rare mitotic activity; no / rare nuclear atypia, but may have atypical bizarre stromal cells (Mod Pathol 2007;20:148, Ann Diagn Pathol 2008;12:328)
Microscopic (histologic) images
Contributed by Kenneth A. Iczkowski, M.D.
Leiomyoma
Positive stains
- Desmin, actin, androgen receptor
Differential diagnosis
- Nodular hyperplasia: no well organized fascicles, no hyalinization, no necrosis, no calcification
- Leiomyosarcoma: hypercellular, infiltrative, variable atypia, definite mitotic activity, necrosis
