Prostate gland & seminal vesicles

Other nonneoplastic lesions

Paneth cell-like change



Topic Completed: 1 July 2012

Minor changes: 3 September 2020

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PubMed search: Prostatic paneth cell-like change

Monika Roychowdhury, M.D.
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Cite this page: Roychowdhury M. Paneth cell-like change. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/prostatepaneth.html. Accessed December 8th, 2021.
Definition / general
Positive stains
  • PAS+ diastase resistant (benign epithelium), neuroendocrine markers (dysplastic / malignant epithelium), PSA
Negative stains
  • Lysozyme
Electron microscopy description
  • Exocrine-like or lysosomal-like vesicles in benign epithelium, neuroendocrine granules in dysplastic / malignant epithelium
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