Prostate gland & seminal vesicles
Seminal vesicles
Seminal vesicles-carcinoma


Topic Completed: 1 July 2012

Minor changes: 13 July 2020

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed search: prostatic seminal vesicle carcinoma

Komal Arora, M.D.
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Page views in 2020 to date: 491
Cite this page: Arora K. Seminal vesicles-carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/prostatesemca.html. Accessed August 13th, 2020.
Definition / general
  • Very rare, must confirm microscopically
  • Primary tumors should be localized primarily to seminal vesicle; must rule out invasion from prostate (do PSA / PAP), rectum or other sites
  • Usually a papillary adenocarcinoma resembling architecture of normal seminal vesicle
  • Resembles prostatic duct adenocarcinoma Gleason patterns 3 or 4 or mucinous (colloid) carcinoma
  • Usually unresectable and patients die within 2 years
  • Adenocarcinoma: very rare, must rule out prostate primary; often mucin producing, ulcerates through skin of scrotum
Case reports
Gross images

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Low grade epithelial stromal tumor

Microscopic (histologic) images

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Metastatic hepatocellular carcinoma

Low grade epithelial stromal tumor

Positive stains
Negative stains
Differential diagnosis
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