Prostate gland & seminal vesicles

Seminal vesicles

Carcinoma of seminal vesicle

Topic Completed: 1 July 2012

Minor changes: 30 October 2020

Copyright: 2003-2021,, Inc.

PubMed search: prostatic seminal vesicle carcinoma

Komal Arora, M.D.
Page views in 2020: 813
Page views in 2021 to date: 948
Cite this page: Arora K. Carcinoma of seminal vesicle. website. Accessed December 7th, 2021.
Definition / general
  • Very rare, must confirm microscopically
  • Primary tumors should be localized primarily to seminal vesicle; must rule out invasion from prostate (do PSA / PAP), rectum or other sites
  • Usually a papillary adenocarcinoma resembling architecture of normal seminal vesicle
  • Resembles prostatic duct adenocarcinoma Gleason patterns 3 or 4 or mucinous (colloid) carcinoma
  • Usually unresectable and patients die within 2 years
  • Adenocarcinoma: very rare, must rule out prostate primary; often mucin producing, ulcerates through skin of scrotum
Case reports
Gross images

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Low grade epithelial stromal tumor

Microscopic (histologic) images

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Metastatic hepatocellular carcinoma

Low grade epithelial stromal tumor

Positive stains
Negative stains
Differential diagnosis
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