Prostate gland & seminal vesicles

Seminal vesicles


Last author update: 1 July 2012
Last staff update: 14 October 2022

Copyright: 2003-2023,, Inc.

PubMed search: prostatic seminal vesicle carcinoma

Komal Arora, M.D.
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Cite this page: Arora K. Adenocarcinoma. website. Accessed September 30th, 2023.
Definition / general
  • Very rare, must confirm microscopically
  • Primary tumors should be localized primarily to seminal vesicle; must rule out invasion from prostate (do PSA / PAP), rectum or other sites
  • Usually a papillary adenocarcinoma resembling architecture of normal seminal vesicle
  • Resembles prostatic duct adenocarcinoma Gleason patterns 3 or 4 or mucinous (colloid) carcinoma
  • Usually unresectable and patients die within 2 years
  • Adenocarcinoma: very rare, must rule out prostate primary; often mucin producing, ulcerates through skin of scrotum
Case reports
Gross images

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Low grade epithelial stromal tumor

Microscopic (histologic) images

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Metastatic hepatocellular carcinoma

Low grade epithelial stromal tumor

Positive stains
Negative stains
Differential diagnosis
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