Salivary glands
Primary salivary gland neoplasms
Benign
Salivary duct papilloma


Topic Completed: 1 September 2012

Minor changes: 2 November 2020

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PubMed Search: Salivary duct papilloma

Adriana Handra-Luca, M.D.
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Cite this page: Handra-Luca A. Salivary duct papilloma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/salivaryglandssalivaryductpap.html. Accessed March 5th, 2021.
Definition / general
  • Rare, benign papillary proliferations of bland cuboidal / columnar epithelial cells with fibrovascular cores, inflammation
  • Also called intraductal papilloma, intraductal papillary tumor
  • Usually in minor salivary glands, rare in parotid or sublingual glands
Clinical features
Case reports
Treatment
  • Surgery; does not recur.
Microscopic (histologic) description
  • Papillary proliferations of bland cuboidal / columnar epithelial cells with fibrovascular cores, inflammation, few mitoses
  • May have acinar cell differentiation, ductal cyst by obliteration, malignant transformation to adenocarcinoma
Microscopic (histologic) images

Images hosted on other servers:

Upper lip tumor has papillary
proliferation of epithelial
cells with branching fronds
in cystically dilated duct lumen

Cytology description
  • Compact clusters of papillary monomorphic columnar cells with abundant finely vacuolar cytoplasm; oval nuclei basally located, indistinct nucleol; no squamous cells (Acta Cytol 1999;43:457)
Positive stains
Negative stains
Electron microscopy images

Images hosted on other servers:

A: secretary granules, rough endoplasmic reticulum, golgi apparatus
and mitochondria; B: microvilli on luminal surface of epithelial cells
appear to be secretory; C: annulate lamellae composed of parallel
arrays of cisternae have small annuli or fenestrae

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