Skin melanocytic tumor
Other pigmented lesions and disorders of pigmentation
Paraganglioma-like dermal melanocytic tumor

Topic Completed: 1 April 2013

Minor changes: 4 April 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Paraganglioma-like dermal melanocytic tumor

Christopher S. Hale, M.D.
Page views in 2019: 371
Page views in 2020 to date: 81
Cite this page: Hale C Paraganglioma-like dermal melanocytic tumor. website. Accessed June 1st, 2020.
Definition / general
  • Very rare; 8 of 30,000 consultation cases in one series
  • 75% females, mean age 35 years (range 18 - 53 years)
Clinical features
  • Dermal nodule, mean 1 cm
Case reports
Microscopic (histologic) description
  • Nested growth pattern similar to paraganglioma, composed of clear to amphophilic oval cells separated by delicate fibrous strands
  • No / mild nuclear atypia
  • 1 - 4 MF / 10 HPF
  • No melanin
  • Normal epidermis, no junctional activity
Microscopic (histologic) images

Images hosted on other servers:

Well demarcated nodule in dermis with normal epidermis

Tumor restricted to deep dermis


Various images

Neoplasm composed of organoid and nested groups of large epithelioid cells,
separated by delicate fibrous strands and prominent blood vessels; epithelioid
cells have somewhat clear cytoplasm, large nuclei with prominent red nucleoli

Positive stains
Negative stains
Molecular / cytogenetics description
Differential diagnosis
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