Skin nonmelanocytic tumor

Lymphoma and related disorders (see also Lymphoma chapter)

Cutaneous T cell lymphoma (CTCL)

Mycosis fungoides special variants



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PubMed search: Mycosis fungoides variants [title]

Christopher S. Hale, M.D.
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Cite this page: Hale CS. Mycosis fungoides special variants. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticMFspecialvariants.html. Accessed March 28th, 2024.
Pagetoid reticulosis
  • Indolent, T cell cutaneous proliferative disorder related to mycosis fungoides
  • Also called Woringer-Kolopp disease; disseminated lesions called Ketron-Goodman disease
  • 2:1 male to female incidence
  • Usually solitary lesion on distal extremities
  • Treatment may include electron beam, pharmacological intervention, psoralen plus ultraviolet A (PUVA) photochemotherapy, radiotherapy, or surgery (J Clin Aesthet Dermatol 2010;3:46)
  • Solitary erythematosquamous patch with monomorphic intraepidermal infiltrate of mycosis fungoides-like cells, in Paget's disease type pattern
Other variants
  • Special variants to be added include the WHO-EORTC variants including folliculotropic/adnexotropic MF and granulomatous slack skin syndrome. Rarer variants like pigmented purpura-like etc can be mentioned
Case reports
Clinical images

Images hosted on other servers:

Pagetoid reticulosis: 10 × 10mm plaque

Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.

Pagetoid reticulosis



Images hosted on other servers - pagetoid reticulosis:

Psoriasiform hyperplasia

CD8, CD4

Positive stains
  • Pagetoid reticulosis: either CD4+ CD8+ or CD4- CD8-
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