Skin nonmelanocytic tumor
Premalignant / in situ
Bowenoid papulosis
Author: Christopher S. Hale, M.D.
Topic Completed: 1 June 2012
Minor changes: 14 October 2020
Copyright: 2002-2021, PathologyOutlines.com, Inc.
PubMed Search: Bowenoid papulosis
Table of Contents
Definition / general | Case reports | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Molecular / cytogenetics description | Differential diagnosisCite this page: Hale C. Bowenoid papulosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticbowenoidpapulosis.html. Accessed October 20th, 2021.
Definition / general
- Multiple pigmented papular lesions of anogenital area, usually in young adults, resembling condyloma acuminatum
- May regress spontaneously
- Almost never invasive
Case reports
- Two patients treated by Tazarotene (Indian J Dermatol 2009;54:283)
Clinical images
Images hosted on other servers:
Penile shaft
Gross description
- Flat papules on anogenital skin
Microscopic (histologic) description
- Resembles carcinoma in situ, but with localized acanthosis similar to condylomas
- Low power view is “salt and pepper” due to dark nuclei and clear vacuolar cytoplasm
- Usually no adnexal involvement
Microscopic (histologic) images
Images hosted on other servers:
Acanthosis and dyskeratosis
Positive stains
Molecular / cytogenetics description
- HPV type 16 is most common
Differential diagnosis
