Skin nonmelanocytic tumor
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands)
Eccrine spiradenoma
Author: Christopher S. Hale, M.D.
Topic Completed: 1 June 2012
Minor changes: 4 April 2019
Copyright: 2002-2016, PathologyOutlines.com, Inc.
PubMed Search: Eccrine spiradenoma [title]
Table of Contents
Definition / general | Case reports | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Electron microscopy description | Differential diagnosisCite this page: Hale C. Eccrine spiradenoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticeccrinespiradenoma.html. Accessed August 11th, 2020.
Definition / general
- Extremely painful lesions, anywhere in body
- Rarely transforms to high grade malignancy
Case reports
- 73 year old with facial lesion (Indian J Dermatol Venereol Leprol 2008;74:541)
Clinical images
Images hosted on PathOut server:
Breast skin, courtesy of Mark R. Wick, M.D.
Gross description
- Painful, slow growing solitary nodule, head/neck, adults > children
- Occasional multiple lesions, linear or Blaschkoid distribution
Microscopic (histologic) description
- Sharply circumscribed, lobular
- Very cellular
- Cells have scant cytoplasm
- High vascularity
- Variable lymphocytic infiltrate within lesion
Microscopic (histologic) images
Images hosted on PathOut servers:
57 year old woman with mass in axillary lymph node, Contributed by Stephanie Liu, D.O.
Contributed by Dr. Amy Lynn
Breast skin, courtesy of Mark R. Wick, M.D.
Images hosted on Flickr:
Eccrine spiradenoma
Electron microscopy description
- Epithelial and myoepithelial cells
Differential diagnosis
- Cutaneous lymphadenoma
- Cylindroma
- Metastatic carcinoma
- Synovial sarcoma
- Thymoma
