Skin nonmelanocytic tumor
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands)
Eccrine spiradenoma

Topic Completed: 1 June 2012

Minor changes: 4 April 2019

Copyright: 2002-2016,, Inc.

PubMed Search: Eccrine spiradenoma [title]

Christopher S. Hale, M.D.
Page views in 2019: 18,668
Page views in 2020 to date: 9,437
Cite this page: Hale C. Eccrine spiradenoma. website. Accessed August 11th, 2020.
Definition / general
  • Extremely painful lesions, anywhere in body
  • Rarely transforms to high grade malignancy
Case reports
Clinical images

Images hosted on PathOut server:

Breast skin, courtesy of Mark R. Wick, M.D.

Gross description
  • Painful, slow growing solitary nodule, head/neck, adults > children
  • Occasional multiple lesions, linear or Blaschkoid distribution
Microscopic (histologic) description
  • Sharply circumscribed, lobular
  • Very cellular
  • Cells have scant cytoplasm
  • High vascularity
  • Variable lymphocytic infiltrate within lesion
Microscopic (histologic) images

Images hosted on PathOut servers:

57 year old woman with mass in axillary lymph node, Contributed by Stephanie Liu, D.O.

Contributed by Dr. Amy Lynn

Breast skin, courtesy of Mark R. Wick, M.D.

Images hosted on Flickr:

Eccrine spiradenoma

Electron microscopy description
  • Epithelial and myoepithelial cells
Differential diagnosis
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