Skin nonmelanocytic tumor
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands)
Microcystic adnexal carcinoma
Author: Christopher S. Hale, M.D.
Last author update: 1 June 2012
Last staff update: 6 November 2020
Copyright: 2002-2023, PathologyOutlines.com, Inc.
PubMed Search: Microcystic adnexal carcinoma [title]
Table of Contents
Definition / general | Case reports | Gross description | Gross images | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Hale C. Microcystic adnexal carcinoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticsclerosingsweatductcarcinoma.html. Accessed March 24th, 2023.
Definition / general
- Also called sclerosing sweat gland carcinoma
- Slow growing nodule or plaque, usually on upper lip or face
- Difficult to achieve negative surgical margins, commonly recurs, metastases very rare
- Perineural invasion common
Case reports
- 57 year old Japanese man with facial plaque (Acta Derm Venereol 2012;92:109)
Gross description
- Slow-growing facial plaque
Gross images
Images hosted on other servers:
Large, hard-rubbery neoplasm
Microscopic (histologic) description
- Cords and nests of bland keratinocytes, keratin cysts and ductal differentiation
- Dense collagenous stroma
- Is invasive, may extend into subcutis or perineural spaces
- Resembles syringoma
- Rarely is sebaceous differentiation
Microscopic (histologic) images
Contributed by Mark R. Wick, M.D.
Differential diagnosis
