Skin nonmelanocytic tumor

Lymphoma and related disorders (see also Lymphoma chapter)

T cell / NK cell neoplasms

Pagetoid reticulosis

Topic Completed: 1 July 2012

Minor changes: 8 December 2020

Copyright: 2003-2021,, Inc.

PubMed search: Woringer-Kolopp disease [title]

Christopher S. Hale, M.D.
Page views in 2020: 803
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Cite this page: Hale CS. Pagetoid reticulosis. website. Accessed December 4th, 2021.
Definition / general
  • Indolent, T cell cutaneous proliferative disorder related to mycosis fungoides
  • 2:1 male to female incidence
  • Usually solitary lesion on distal extremities
  • Disseminated lesions called Ketron-Goodman disease
  • Also called Woringer-Kolopp disease
Case reports
  • May include electron beam, pharmacological intervention, psoralen plus ultraviolet A (PUVA) photochemotherapy, radiotherapy, or surgery (J Clin Aesthet Dermatol 2010;3:46)
Clinical images

Images hosted on other servers:

10 × 10mm plaque

Gross description
  • Solitary erythematosquamous patch
Microscopic (histologic) description
  • Monomorphic intraepidermal infiltrate of mycosis fungoides-like cells, in Paget's disease type pattern
Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.

Images hosted on other servers:

Psoriasiform hyperplasia

CD8, CD4

Positive stains
  • Either CD4+ CD8+ or CD4- CD8-
Differential diagnosis
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