Small intestine & ampulla
Inflammatory disorders
Eosinophilic enteritis / gastroenteritis
Author: Hanni Gulwani, M.B.B.S.
Topic Completed: 1 August 2012
Minor changes: 19 January 2021
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PubMed Search: Eosinophilic enteritis gastroenteritis small bowel
Table of Contents
Definition / general | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Gulwani H. Eosinophilic enteritis / gastroenteritis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/smallboweleosinophilic.html. Accessed March 4th, 2021.
Definition / general
- Rare disease that may present as obstruction, associated with peripheral eosinophilia and allergic symptoms in children or young adults (Rev Esp Enferm Dig 2004;96:279, Ann Acad Med Singapore 2011;40:379, Ital J Pediatr 2011;37:18)
- Nausea, vomiting, diarrhea, steatorrhea, protein losing enteropathy
- Symptoms are related to site of infiltration: mucosa of stomach / small bowel - diarrhea and malabsorption; submucosa and muscularis propria - obstruction; subserosa - ascites
Microscopic (histologic) description
- Marked eosinophilic infiltration of bowel wall (> 20 eosinophils/HPF in at least one focus), prominent vessels, occasionally necrotizing granulomas and vasculitis
- Eosinophils typically not associated with other inflammatory cells
- Infiltration may be patchy
Microscopic (histologic) images
Images hosted on other servers:
Various images
Differential diagnosis
- Ancylostoma caninum infection
- Collagen vascular disease
- Inflammatory bowel disease
- Lymphoma
- Sarcocystis infection
