Small bowel (small intestine)
Other malignancies
Metastases to small bowel


Topic Completed: 1 August 2012

Minor changes: 4 April 2020

Copyright: 2003-2020, PathologyOutlines.com, Inc.

PubMed Search: Metastases to small bowel[TI]

Hanni Gulwani, M.B.B.S.
Page views in 2019: 144
Page views in 2020 to date: 86
Cite this page: Gulwani H. Metastases. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/smallbowelmetastases.html. Accessed May 24th, 2020.
Definition / general
  • Often appear as multiple polypoid tumors causing obstruction or perforation
  • Usually melanoma, lung carcinoma, breast carcinoma, choriocarcinoma
  • Melanoma: often long period between primary and metastatic diagnosis; better prognosis if solitary versus multiple metastases
Case reports
Gross images

Contributed by Dr. Semir Vranić, University of Sarajevo, Bosnia and Herzegovina

Gallbladder carcinosarcoma: metastatic to small bowel



Images hosted on other servers:

Osteosarcoma metastatic to jejunum

Metastasis - site of origin not specified

Metastatic cutaneous melanoma to jejunum

Microscopic (histologic) description
  • Melanoma: undifferentiated tumor with discohesive cells with pink cytoplasm, pleomorphic nuclei, macronucleoli, frequent mitotic figures; spindled or epithelioid cells
Microscopic (histologic) images

Contributed by Dr. Semir Vranić, University of Sarajevo, Bosnia and Herzegovina

Melanoma from thigh of 50 year old Bosnian man metastatic to jejunum (H&E, S100, MelanA)



Images hosted on other servers:

Metastatic leiomyosarcoma

Metastatic osteosarcoma

Various images

Positive stains
Negative stains
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