Small intestine & ampulla

Benign tumors / tumor-like conditions

Neuromuscular and vascular hamartoma of small bowel

Topic Completed: 1 August 2012

Minor changes: 19 November 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Neuromuscular and vascular hamartoma of small bowel

Hanni Gulwani, M.B.B.S.
Page views in 2020: 620
Page views in 2021 to date: 1,138
Cite this page: Gulwani H. Neuromuscular and vascular hamartoma of small bowel. website. Accessed December 6th, 2021.
Definition / general
  • Also called small bowel hamartoma
  • Similar to diaphragm disease (annular constrictions causing small bowel obstruction associated with NSAIDs) but without NSAID association (Am J Surg Pathol 1999;23:1414)
Case reports
Gross description
  • Multiple circumferential indentions of serosa corresponding to discrete ridges on mucosal surface
Microscopic (histologic) description
  • Ridges composed of submucosa only, contain proliferating blood vessels surrounded by smooth muscle fibers originating from a frayed muscularis mucosa
  • Variable nerve and ganglionic cells present in fibrous collagenous tissue
  • No / minimal inflammatory infiltrate
Microscopic (histologic) images

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