Small intestine & ampulla

Infectious disorders

Strongyloides stercoralis

Last author update: 1 August 2012
Last staff update: 17 March 2022

Copyright: 2002-2023,, Inc.

PubMed Search: Strongyloides stercoralis[TI] small bowel

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Strongyloides stercoralis. website. Accessed April 1st, 2023.
Definition / general
  • Nematode with complex life cycle that alternates between free living and parasitic cycles, with potential for autoinfection and multiplication within host
Life cycle
  • Larvae burrow into mucosa of duodenum and jejunum, where they mature into adults
  • Females lay eggs, which develop into larvae that pass into stool, where they mature and become infective
  • Infective larvae in soil penetrate intact skin, usually through feet
  • Larvae enter circulatory system, are transported to lungs, enter alveolar spaces, are carried to trachea and pharynx, are swallowed and enter intestinal tract, where process is repeated
  • If larvae become infective before leaving body, they may invade intestinal mucosa or perianal skin, causing autoinfection
Diagrams / tables

Images hosted on other servers:

Life cycle

Clinical features
  • Symptoms: none, diarrhea, malabsorption
  • Severe / fatal infections in immunocompromised, due to worms moving from GI tract into other organs (WormBook 2007:1)
  • Larvae in stool
  • Adult female or eggs in small bowel mucosa, often with eosinophilic or granulomatous inflammation
Case reports
Microscopic (histologic) images

Contributed by Josehp Christopher Castillo, M.D. and Case #133

Small intestine

Various images

Contributed by @liverwei on Twitter
Strongyloides stercoralis Strongyloides stercoralis Strongyloides stercoralis

Strongyloides stercoralis

Additional references
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