Small intestine & ampulla

Infectious disorders

Tuberculosis



Topic Completed: 1 August 2012

Minor changes: 19 March 2021

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PubMed Search: Tuberculosis[TI] small bowel[TIAB]

Hanni Gulwani, M.B.B.S.
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Cite this page: Gulwani H. Tuberculosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/smallboweltuberculosis.html. Accessed December 8th, 2021.
Definition / general
  • Disease occasionally seen in less developed countries
  • Small intestinal disease may be transmitted via contaminated milk
  • Symptoms: abdominal pain, malabsorption, strictures, perforation, fistula
Sites
  • Terminal ileum, cecum, appendix
Gross description
  • Multiple and circumferential ulcers and strictures
Microscopic (histologic) description
  • Confluent granulomas with central necrosis and peripheral lymphocytosis
  • Destruction of muscularis propria, scarring
Microscopic (histologic) images

Contributed by Hanni Gulwani, M.B.B.S.

Ileocecal tuberculosis in 45 year old woman; epithelioid granulomas with Langhans giant cells in lamina propria


Ileocecal tuberculosis and adjoining draining lymph node



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Granulomas in mucosa and submucosa

Positive stains
Differential diagnosis
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