Soft tissue
Adipose tissue
Multiple symmetric lipomatosis

Topic Completed: 1 June 2012

Minor changes: 20 March 2019

Copyright: 2002-2018,, Inc.

PubMed Search: Multiple symmetric lipomatosis

See also: lipomatosis, adiposis dolorosa

Page views in 2019: 288
Page views in 2020 to date: 92
Cite this page: Singh C. Multiple symmetric lipomatosis. website. Accessed May 24th, 2020.
Definition / general
  • Multiple non-encapsulated lipomas with symmetric distribution and sparing of distal arms and legs
  • Also called Madelung’s disease, Launois-Bensaude syndrome, benign symmetric lipomatosis
Case reports
Clinical images

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Launois-Bensaude's lipomatosis

Two patients with multiple symmetric lipomatosis (MSL)

Gross description
  • Involves subcutaneous and deep soft tissue
Gross images

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Neck tumor

Microscopic (histologic) description
  • Unencapsulated masses of mature adipose tissue
Microscopic (histologic) images

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Resembling well differentiated liposarcoma

Adipose surrounding nerve

Molecular / cytogenetics description
Additional references
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