Cite this page: Arora K. Angiofibroma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/softtissueangiofibroma.html. Accessed August 3rd, 2020.
- 38 year old woman with ankle mass (Case of the Week #311)
- Cellular angiofibroma: usually in genital region, more cellular, usually ER+, PR+
- Low grade fibromyxoid sarcoma: often > 6 cm and infiltrative, 45% have epithelioid areas, 40% contain poorly formed but large collagen rosettes
- Low grade myxofibrosarcoma: infiltrative borders, often sends out long tentacles, more solid areas are often seen similar to typical undifferentiated pleomorphic sarcom; has curvilinear vessels (thick walled with broad arc) with condensation of cells around vessels
- Myxoid liposarcoma: prominent chicken wire vasculature, numerous signet ring lipoblasts particularly at periphery of lobules, mucoid matrix rich in hyaluronidase sensitive acid mucopolysaccharides, may have large mucoid pools, S100+
- Solitary fibrous tumor: fibroblast like cells with patternless pattern, thick bands of collagen and prominent branching, hyalinized vessels; CD34+, CD99+