Soft tissue

Vascular

Nonneoplastic

Bacillary angiomatosis



Topic Completed: 1 November 2012

Minor changes: 7 December 2020

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PubMed Search: Bacillary angiomatosis [title] soft tissue

Vijay Shankar, M.D.
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Cite this page: Shankar V. Bacillary angiomatosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/softtissuebacillary.html. Accessed October 15th, 2021.
Definition / general
  • Opportunistic infection of immunocompromised, first described in AIDS, manifesting as vascular proliferations in bone, CNS, skin, other organs
  • Rarely imunocompetent individuals (Indian J Dermatol Venereol Leprol 2010;76:682)
  • Caused by infection with Bartonella species (gram negative rods), either Bartonella henselae (causes cat-scratch disease, reservoir in cats, vector is cat flea), B. quintana (cause of trench fever during WW I, reservoir in humans, vector is human body louse) or other species; transmitted via traumatic inoculation of skin
  • Bacillary peliosis: related vascular lesion of liver and spleen
Case reports
Treatment
  • Erythromycin
Clinical images

Contributed by Mark R. Wick, M.D.
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Palm, simulating pyogenic granuloma



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Skin: nodules with ulceration

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Skin: at site of burn

Gross description
  • Moist, eruptive, cutaneous lesion
Microscopic (histologic) description
  • Acute neutrophilic inflammation with vascular proliferation and prominent endothelial cells with nuclear atypia and mitotic figures
  • Nuclear dust and granular material (bacteria) present
  • Bacteria highlighted by silver stain
Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.
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Dermal lobular vascular proliferation with swollen endothelial cells and bacteria (Warthin-Starry)

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Mixed inflammation, capillary proliferation

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