Table of Contents
Definition / generalCite this page: Arora K. Cell types. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/softtissuecelltypes.html. Accessed February 3rd, 2023.
Definition / general
Epithelioid:
Pleomorphic:
Round cell:
Spindle cell:
- Alveolar soft parts sarcoma, carcinoma (extension into soft tissue or metastases), clear cell sarcoma, epithelioid histiocytoma, epithelioid sarcoma, epithelioid variant of leiomyosarcoma, MFH or MPNST
- Extracellular myxoid chondrosarcoma, myxofibrosarcoma, rhabdoid tumor, schwannoma, synovial sarcoma or vascular tumors
Pleomorphic:
- Variants of leiomyosarcoma, liposarcoma, MFH, MPNST, myxofibrosarcoma, PHAT, pleomorphic lipoma or rhabdomyosarcoma
- Also melanoma and metastatic carcinoma
Round cell:
- Desmoplastic small round cell sarcoma, Ewings/PNET, mesenchymal chondrosarcoma, MPNST, rhabdomyosarcoma, round cell liposarcoma, schwannoma with neuroblastoma-like features, synovial sarcoma
- Also carcinoma, lymphoma, melanoma, neuroblastoma, poorly differentiated tumors
Spindle cell:
- Angiosarcoma, benign fibrous histiocytoma, benign nerve sheath tumor, DFSP, fibroma of tendon sheath (cellular), fibromatosis, fibrosarcoma, Kaposi’s sarcoma, leiomyoma, leiomyosarcoma, MPNST, nodular fasciitis, spindle cell lipoma, spindle cell variant of embryonal rhabdomyosarcoma, solitary fibrous tumor, superficial acral fibromyxoma, synovial sarcoma