Soft tissue

Extraskeletal bone tumors


Topic Completed: 1 November 2012

Minor changes: 20 November 2020

Copyright: 2002-2021,, Inc.

PubMed Search: Extraskeletal chondrosarcoma [title]

See also: Mesenchymal chondrosarcoma, Myxoid chondrosarcoma

Vijay Shankar, M.D.
Page views in 2020: 4,607
Page views in 2021 to date: 2,645
Cite this page: Shankar V. Chondrosarcoma. website. Accessed October 15th, 2021.
Definition / general
  • Less aggressive than similar bone tumor
  • Usually adult extremities; also children and trunk
  • Metastases to lung
  • Embryonal chondrosarcoma: Rare, primitive appearance
Gross images

Contributed by Mark R. Wick, M.D.


Images hosted on other servers:

Thigh tumor

Fallopian tube tumor

Microscopic (histologic) description
  • Usually myxoid
  • Cords of small cells with acidophilic cytoplasm, occasional vacuoles, usually in myxoid stroma
  • Usually no obvious chondrocytes
Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.

Clear cell

Images hosted on other servers:

Fallopian tube tumor

Positive stains
Negative stains
Electron microscopy description
  • Well developed endoplasmic reticulum, cytoplasmic filaments, glycogen
Molecular / cytogenetics description
  • t(9;22)(q22-31;q11-12): CHN-EWS fusion gene, is consistent marker for extraskeletal myxoid chondrosarcoma (Mod Pathol 1995;8:765)
Back to top
Image 01 Image 02