Soft tissue



Microvenular hemangioma

Last author update: 1 November 2012
Last staff update: 22 December 2021

Copyright: 2003-2022,, Inc.

PubMed search: Microvenular hemangioma

Vijay Shankar, M.D.
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Cite this page: Shankar V. Microvenular hemangioma. website. Accessed August 14th, 2022.
Definition / general
  • Dermal proliferation of small, irregular branching capillaries and venules with inconspicuous lumina
  • Rare; < 50 cases reported
  • Young to middle aged adults
  • Often trunk or limbs
  • May be form of acquired venous hemangioma
  • Microcapillary hemangioma: similar histology, but occurs in young women taking oral contraceptives or during pregnancy
Clinical features
Case reports
  • Excision is curative
Gross images

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Well defined, oval red lesion

Microscopic (histologic) description
  • Dermal proliferation of small, irregular branching capillaries and venules with inconspicuous lumina
  • Endothelial cells may be plump, but no atypia
  • Stroma is collagenous
  • Variable lymphocytes
  • No fat invasion, although may grow along collagenous septa of subcutis
  • No spindle cells
Microscopic (histologic) images

Case #80

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Dermal vascular proliferation

Positive stains
Differential diagnosis
  • Acquired (tufted) angioma: multiple vascular lobules similar to pyogenic granuloma but more cellular, resembling cannonballs
  • Kaposi's sarcoma - patch stage: irregular vascular spaces are anastomosing but not collapsed, and are accompanied by atypical endothelial cells, eosinophilic hyaline globules, plasma cells and fascicles of spindle cells; may be irregular dissection of collagen bundles by vessels; spindle cells are HHV8+, patients are HIV+ (Am J Clin Pathol 2004;121:335)
  • Kaposiform hemangioendothelioma: also has slit-like lumina, but they are due to nodules and sheets of compact spindle cells; affects the skin or retroperitoneum of infants and children, may be associated with severe coagulopathy
  • Sclerosing hemangioma
  • Statis related change
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