Soft tissue

Topic Completed: 1 November 2012

Minor changes: 17 September 2020

Copyright: 2002-2021,, Inc.

PubMed Search: Nerve [title] soft tissue

Vijay Shankar, M.D.
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Table of Contents
Definition / general
Cite this page: Shankar V. Histology-nerve. website. Accessed May 7th, 2021.
Definition / general
  • Composed of axons, Schwann cells, perineurial cells and fibroblasts in epineurium (outer sheath)
  • Perineurium: surrounds each nerve fascicle, is continuous with pia mater of CNS
  • Perineurial cells: derived from fibroblasts; EMA+, S100-
  • Schwann cells: neuroectodermally derived cells that resemble fibroblasts, but strongly S100+, intimately related to axons (by EM), have continuous basal lamina that coats the cell facing the endoneurium
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