Soft tissue
General
Staging-trunk and extremities
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Staging soft tissue sarcomas of trunk and extremities
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Cite this page: Malik F, Clay MR. Staging-trunk and extremities. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/softtissuestagingtrunkextremities.html. Accessed January 30th, 2023.
Pathologic TNM staging of sarcomas of the trunk and extremities, AJCC 8th edition
Primary tumor (pT)
- pTX: Primary tumor cannot be assessed
- pT0: No evidence of primary tumor
- pT1: Tumor ≤ 5 cm in greatest dimension
- pT2: Tumor > 5 cm and ≤ 10 cm in greatest dimension
- pT3: Tumor > 10 cm and ≤ 15 cm in greatest dimension
- pT4: Tumor > 15 cm in greatest dimension
Notes:
- Largest tumor diameter (in any plane) should be measured
- Special consideration should be given to tumors that may have tail-like projections, such as undifferentiated pleomorphic sarcoma and myxofibrosarcoma
- Surrounding edema, if present, should be excluded from size measurement
Regional lymph nodes (pN)
- pN0: No regional lymph node involvement
- pN1: Regional lymph node metastasis
Notes:
- pNX is not used for soft tissue tumors and no pN should be reported if no lymph nodes are present
Histologic grade (G)
- GX: Grade cannot be assessed
- G1: Total differentiation, mitotic count and necrosis score of 2 or 3
- G2: Total differentiation, mitotic count and necrosis score of 4 or 5
- G3: Total differentiation, mitotic count and necrosis score of 6, 7 or 8
AJCC prognostic stage groups
| AJCC stage
| Stage grouping
| Trunk and extremities sarcoma stage
|
| IA
| T1
| Cancer is ≤ 5 cm (2 in) (T1)
|
|
| N0
| It has not spread to nearby lymph nodes (N0)
|
|
| M0
| It has not spread to distant sites (M0)
|
|
| G1 or GX
| Cancer is grade 1 (G1) or the grade cannot be assessed (GX)
|
| IB
| T2, T3, T4
| Cancer is > 5 cm but ≤ 10 cm (T2) OR > 10 cm but ≤ 15 cm (T3) OR > 15 cm (T4)
|
|
| N0
| It has not spread to nearby lymph nodes (N0)
|
|
| M0
| It has not spread to distant sites (M0)
|
|
| G1 or GX
| Cancer is grade 1 (G1) or the grade cannot be assessed (GX)
|
| II
| T1
| Cancer is ≤ 5 cm (2 in) (T1)
|
|
| N0
| It has not spread to nearby lymph nodes (N0)
|
|
| M0
| It has not spread to distant sites (M0)
|
|
| G2 or G3
| Cancer is grade 2 (G2) or grade 3 (G3)
|
| IIIA
| T2
| Cancer is > 5 cm but ≤ 10 cm (T2)
|
|
| N0
| It has not spread to nearby lymph nodes (N0)
|
|
| M0
| It has not spread to distant sites (M0)
|
|
| G2 or G3
| Cancer is grade 2 (G2) or grade 3 (G3)
|
| IIIB
| T3 or T4
| Cancer is > 10 cm but ≤ 15 cm (T3) OR > 15 cm (T4)
|
|
| N0
| It has not spread to nearby lymph nodes (N0)
|
|
| M0
| It has not spread to distant sites (M0)
|
|
| G2 or G3
| Cancer is grade 2 (G2) or grade 3 (G3)
|
| IV
| Any T
| Cancer is any size (any T) AND
|
|
| N1
| It has spread to nearby lymph nodes (N1)
|
|
| M0
| It has not spread to distant sites (M0)
|
|
| Any G
| It can be any grade
|
|
| OR
|
|
| Any T
| Cancer is any size (any T) AND
|
|
| Any N
| It has or has not spread to nearby lymph nodes (any N)
|
|
| M1
| It has spread to distant sites such as the lungs (M1)
|
|
| Any G
| It can be any grade
|
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