Lymph nodes & spleen, nonlymphoid
Spleen-infectious / inflammatory disorders

Topic Completed: 1 October 2012

Minor changes: 4 July 2020

Copyright: 2003-2019,, Inc.

PubMed Search: Spleen[TI] AIDS[TIAB]

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Table of Contents
Definition / general
Cite this page: Mansouri J. AIDS. website. Accessed August 6th, 2020.
Definition / general
  • Prior to highly active antiretroviral therapy (HAART), typical findings were white pulp depletion, hemosiderin deposition, spindle cell proliferation and perivascular hyalinization; also infectious and malignant infiltrates (Mod Pathol 2002;15:406)
  • Post-HAART findings include less frequent white pulp depletion but similar rates of splenic involvement by atypical mycobacteria and CMV in those with systemic disease
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