Table of ContentsGross description | Microscopic (histologic) description | Positive stains | Differential diagnosis
Cite this page: Mansouri J. Chronic myelogenous leukemia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/spleencml.html. Accessed August 6th, 2020.
- Large, dark red, diffuse involvement with no identifiable Malpighian follicles; often infarcts
Microscopic (histologic) description
- Polymorphous infiltrate of myeloid cells in all stages of differentiation
- Mainly affects splenic red pulp cords and sinuses, obliterates white pulp
- Rarely blastic transformation (Richter syndrome)