Cite this page: Mansouri J. Malaria. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/spleenmalaria.html. Accessed October 16th, 2021.
Definition / general
- May result in splenic rupture, infarction or rarely sudden death, especially with infection by Plasmodium falciparum (Leg Med (Tokyo) 2012;14:111)
- Sudden unexplained death with malaria P. falciparum infection (J Forensic Sci 2010;55:835)
Microscopic (histologic) description
- Hallmark finding is vascular congestion with adherence to endothelial wall by parasitized red blood cells, macrophages contain brown malarial pigment, disorganized architecture with loss of marginal zone and ill defined T cell zones (Cell Microbiol 2012;14:343)