Lymph nodes & spleen, nonlymphoma

Topic Completed: 1 October 2012

Minor changes: 2 November 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Spleen rupture[TI]

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Page views in 2021 to date: 180
Cite this page: Mansouri J. Rupture. website. Accessed January 22nd, 2021.
Definition / general
  • Due to blunt trauma or abdominal surgery, causing hemoperitoneum and emergency splenectomy
  • Only rarely ruptures spontaneously (associated with acute splenitis, amyloidosis [rare], infectious mononucleosis, inflammatory disorders, leukemia / lymphoma, malaria, other tumors, peliosis lienis, pregnancy, subacute bacterial endocarditis, typhoid fever)
  • Splenic rupture may be delayed after trivial / minor trauma
Case reports
Clinical images

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Grossly enlarged with hematoma

Gross description
  • Rupture may be a very small capsular tear, often in superior pole or hilum
Microscopic (histologic) description
  • Neutrophils below capsular tear with intraparenchymal hemorrhage; also lymphoid hyperplasia with prominent marginal zone
Additional references
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