Table of Contents
Definition / general | Case reports | Clinical images | Gross description | Microscopic (histologic) description | Additional referencesCite this page: Mansouri J. Rupture. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/spleenrupture.html. Accessed January 22nd, 2021.
Definition / general
- Due to blunt trauma or abdominal surgery, causing hemoperitoneum and emergency splenectomy
- Only rarely ruptures spontaneously (associated with acute splenitis, amyloidosis [rare], infectious mononucleosis, inflammatory disorders, leukemia / lymphoma, malaria, other tumors, peliosis lienis, pregnancy, subacute bacterial endocarditis, typhoid fever)
- Splenic rupture may be delayed after trivial / minor trauma
Case reports
- 16 year old girl with infectious mononucleosis (Int J Surg Case Rep 2012;3:97)
- 29 year old woman with splenic pregnancy (Arch Pathol Lab Med 2004;128:e146)
- 54 year old woman with systemic lupus erythematosus (Clin Rheumatol 2012;31:1019)
- 2 patients with pancreatic cancer presenting with splenic rupture (Arch Pathol Lab Med 2004;128:1146)
Clinical images
Images hosted on other servers:
Grossly enlarged with hematoma
Gross description
- Rupture may be a very small capsular tear, often in superior pole or hilum
Microscopic (histologic) description
- Neutrophils below capsular tear with intraparenchymal hemorrhage; also lymphoid hyperplasia with prominent marginal zone
Additional references
