Stains & molecular markers

Topic Completed: 1 July 2013

Minor changes: 11 December 2020

Copyright: 2003-2021,, Inc.

PubMed Search: BG8

Nat Pernick, M.D.
Page views in 2020: 442
Page views in 2021 to date: 15
Cite this page: Pernick N, Hamilton K. BG8. website. Accessed January 18th, 2021.
Definition / general
  • Also called Anti-Lewis-Y or Lewis Y antigen, BG-8
  • Mechanism: detects the Lewis Y antigen, type 2 chain
  • Note: Methylobacter albus BG8 is a gram negative bacteria using methane as its carbon source
  • Interpretation: cytoplasmic staining, diffuse and intense
  • Uses by pathologists
    Positive staining - disease
    Negative staining
    • Mesothelioma (sometimes focal or weak staining in epithelium)
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