Stains & CD markers

Last author update: 1 November 2013
Last staff update: 23 June 2021

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PubMed Search: Albumin[TI] free full text[SB] pathology stain

Nat Pernick, M.D.
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Cite this page: Pernick N. Albumin. website. Accessed June 2nd, 2023.
Definition / general
  • Most common serum protein
    • 65K protein produced by ALB gene on #4, by liver (Wikipedia)
    • 50% of total plasma protein content; usual serum concentration of 40 g/L
    • Binds to water, bilirubin, calcium, fatty acids, hormones (acts as carrier protein), potassium, sodium, and various drugs
    • Main function of serum albumin is to regulate blood colloidal osmotic pressure
    • Bovine serum albumin (BSA): plasma protein from cows that maintains osmotic pressure in blood plasma for proper distribution of body fluids between intravascular compartments and body tissues
  • Rarely used as IHC marker for liver
Clinical features
Microscopic (histologic) images

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Left: normal liver; right: negative control

Liver and hepatocellular carcinoma

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