Apolipoprotein D (apoD)

Topic Completed: 1 June 2005

Minor changes: 4 March 2019

Copyright: 2003-2015,, Inc.

PubMed Search: Apolipoprotein D[title]

Nat Pernick, M.D.
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Table of Contents
Definition / general
Cite this page: Pernick N. Apolipoprotein D (apoD). website. Accessed June 2nd, 2020.
Definition / general
  • Member of lipocalin superfamily of proteins involved in transport of cholesterol, steroid hormones and other small hydrophobic molecules
  • Correlates with cell cycle inhibition in various situations including cellular senescence
  • High levels in fibrocystic breast disease and HDL, but produced by almost all tissues in body
  • Expression upregulated in nonneoplastic regenerating peripheral nerve compared to normal, then downregulated during transformation to MPNST (Hum Pathol 2005;36:987)
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