Stains & molecular markers

Topic Completed: 1 May 2016

Minor changes: 16 September 2020

Copyright: 2002-2020,, Inc.

PubMed Search: CAMTA1

Sheren Younes, M.D.
Page views in 2019: 790
Page views in 2020 to date: 937
Cite this page: Younes, S. CAMTA1. website. Accessed October 29th, 2020.
Definition / general
  • Calmodulin binding transcription activator 1 (CAMTA1)
  • Putative tumor suppressor transcription activator
  • Interacts with calmodulin
  • Functions as calcium sensitive regulator of gene expression
Clinical features
Uses by pathologists
Positive stains
  • Staining localization:
    • Nuclear

  • Normal:
  • Disease:
    • Epithelioid hemangioendothelioma
    • 1 of 37 invasive ductal carcinomas showed CAMTA1 positivity
Negative stains
  • Negative in epithelial tumors of bile duct, breast (lobular), endometrium, kidney, liver, lung, ovary, prostate, stomach, thyroid
  • Negative in anaplastic large cell lymphoma, angiosarcoma, epithelioid hemangioma, GIST, melanoma, MPNST, myoepithelioma, PEComa, schwannoma, squamous cell carcinoma, synovial sarcoma, urothelial carcinoma
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