Stains & molecular markers
Cytokeratin 3 (CK3, K3)


Topic Completed: 1 October 2013

Minor changes: 15 December 2020

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PubMed Search: ck3

Nat Pernick, M.D.
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Cite this page: Pernick N. Cytokeratin 3 (CK3, K3). PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsck3.html. Accessed January 20th, 2021.
Definition / general
  • Molecular weight is 64-65 kDa
  • Associates with CK12
  • Mutations in KRT3 gene may cause Meesmann corneal dystrophy (Cornea 2005;24:928)
Uses by pathologists
  • No significant clinical use by pathologists
Positive staining - normal
  • Corneal epithelium (full thickness), limbus epithelium (suprabasal)
Negative staining
  • Conjunctival epithelium
Microscopic (histologic) images

Images hosted on other servers:

Suprabasal staining of
limbus epithelium
cultured using
airlifting technique

Additional references
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