Stains
Cytokeratin 3 (CK3, K3)
Copyright: 2003-2015, PathologyOutlines.com, Inc.
PubMed Search: ck3
Cytokeratin 3 (CK3, K3)
Author: Nat Pernick, M.D.
Topic Completed: 1 October 2013
Minor changes: 4 March 2019
Copyright: 2003-2015, PathologyOutlines.com, Inc.
PubMed Search: ck3
Table of Contents
Definition / general | Uses by pathologists | Positive staining - normal | Negative staining | Microscopic (histologic) images | Additional referencesCite this page: Pernick N. Cytokeratin 3 (CK3, K3). PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsck3.html. Accessed June 2nd, 2020.
Definition / general
- Molecular weight is 64-65 kDa
- Associates with CK12
- Mutations in KRT3 gene may cause Meesmann corneal dystrophy (Cornea 2005;24:928)
Uses by pathologists
- No significant clinical use by pathologists
Positive staining - normal
- Corneal epithelium (full thickness), limbus epithelium (suprabasal)
Negative staining
- Conjunctival epithelium
Microscopic (histologic) images
Suprabasal staining of limbus epithelium cultured using air-lifting (AL) technique (fig A/B)
Additional references
