Stains & molecular markers

Topic Completed: 1 January 2012

Minor changes: 14 December 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Cxcr2 stain

Nat Pernick, M.D.
Page views in 2020: 66
Page views in 2021 to date: 7
Cite this page: Pernick N. CXCR2. website. Accessed January 20th, 2021.
Definition / general
  • Interleukin 8 receptor beta subunit (IL8RB); binds multiple CXC chemokines including IL-8 (CXCL8)
  • Chemokine receptor, powerful neutrophil chemotactic factor, particularly to sites of inflammation
  • Also called CD182; formerly called CD128b
Diagrams / tables

Images hosted on other servers:

Inflammatory infiltration

  • Cytoplasmic staining
Uses by pathologists
  • No significant uses by pathologists
Microscopic (histologic) images

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Ovarian carcinoma

Positive staining - normal
Positive staining - disease
  • Carcinoid tumor (classic, atypical, metastatic), pituitary adenoma, pheochromocytoma, medullary carcinoma
Negative staining
  • Parathyroid cells
  • Small cell carcinoma of lung/cervix, large cell lung neuroendocrine carcinoma, Merkel cell carcinoma, neuroblastoma, melanoma
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