Stains & molecular markers
CXCR2


Topic Completed: 1 January 2012

Minor changes: 3 September 2020

Copyright: 2003-2020, PathologyOutlines.com, Inc.

PubMed Search: Cxcr2 stain

Nat Pernick, M.D.
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Cite this page: Pernick N. CXCR2. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainscxcr2.html. Accessed September 21st, 2020.
Definition / general
  • Interleukin 8 receptor beta subunit (IL8RB); binds multiple CXC chemokines including IL-8 (CXCL8)
  • Chemokine receptor, powerful neutrophil chemotactic factor, particularly to sites of inflammation
Terminology
  • Also called CD182; formerly called CD128b
Diagrams / tables

Images hosted on other servers:

Inflammatory infiltration


Interpretation
  • Cytoplasmic staining
Uses by pathologists
  • No significant uses by pathologists
Microscopic (histologic) images

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Ovarian carcinoma

Positive staining - normal
Positive staining - disease
  • Carcinoid tumor (classic, atypical, metastatic), pituitary adenoma, pheochromocytoma, medullary carcinoma
Negative staining
  • Parathyroid cells
  • Small cell carcinoma of lung/cervix, large cell lung neuroendocrine carcinoma, Merkel cell carcinoma, neuroblastoma, melanoma
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