Home > Stains & CD markers > EBER1 and EBER2
Stains & CD markers
EBER1, EBER2 and LMP

Nat Pernick, M.D.

Last author update: 1 June 2005
Last staff update: 29 July 2022

Copyright: 2002-2023, PathologyOutlines.com, Inc.

PubMed Search: EBER1 / EBER2

Nat Pernick, M.D.
Page views in 2022: 8,146
Page views in 2023 to date: 4,337
Table of Contents
Epstein Barr Virus | EBER1 & EBER2 | LMP | Microscopic (histologic) images
Cite this page: Pernick N. EBER1 and EBER2. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainseber1.html. Accessed June 9th, 2023.
Epstein Barr Virus
  • Strongly associated with sinonasal (NK) lymphomas
  • Associated with monoclonal B cell lymphoproliferative disorder (high grade) and immunosuppression (methotrexate) for autoimmune disease
  • Expresses LMP1, which prevents apoptosis via bcl2 interaction
  • Expresses EBER1, which transactivates host genes
EBER1 & EBER2
  • EBV encoded RNA
    • Nuclear RNA portions of EBER1 and 2 genes
  • Interpretation: nuclear stain
LMP
  • Latent Membrane Protein of EBV
  • Interpretation: cytoplasmic or membranous staining
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.
Missing Image   Missing Image   Missing Image

EBER ISH, high power

Missing Image

LMP in EBV+ nasopharyngeal carcinoma

Back to top
Home > Stains & CD markers > EBER1 and EBER2
Image 01 Image 02