Stains & molecular markers
Giemsa stain

Topic Completed: 1 October 2013

Minor changes: 16 December 2020

Copyright: 2003-2021,, Inc.

PubMed Search: Giemsa stain

Nat Pernick, M.D.
Page views in 2020: 3,126
Page views in 2021 to date: 132
Cite this page: Pernick N. Giemsa stain. website. Accessed January 16th, 2021.
Definition / general
  • As a hematology stain, works best with alcohol fixed smears
  • As a histology stain, detects mast cells and microorganisms, such as Giardia or Helicobacter
  • A "Romanowsky-type" stain, composed of mixtures of methylene blue, azure, and eosin compounds
  • Methylene blue is a metachromatic stain, meaning that some tissue components (mast cell granules, cartilage, mucin, amyloid) stain purple and not blue
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.

H. pylori

Back to top
Image 01 Image 02