Cite this page: Pernick N. Hales colloidal iron. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainshales.html. Accessed June 7th, 2020.
Definition / general
- Kidney tumors: stain must have pH between 1.5 and 2.0
- Clear cell and papillary renal carcinoma have focal, coarse, droplike staining
- Note: hemosiderin in any tumors will also stain positive
Uses by pathologists
- Helpful in distinguishing chromophobe renal cell carcinoma (intensely positive in large percentage of cells with reticular staining) from oncocytoma (usually negative; if positive - fewer cells with less intensity and dustlike staining)