Stains & molecular markers
HBME
Topic Completed: 1 June 2005
Minor changes: 10 December 2020
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HBME
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Definition / general
- Also called HBME-1
- Marker of mesothelial cells, named after laboratory of Dr. Hector Battifora and MEsothelioma
- Also positive in various thyroid carcinomas
Microscopic (histologic) images
Contributed by Andrey Bychkov, M.D., Ph.D.
Tumor interface
Striking membranous staining
Strong membranous HBME-1 immunoreactivity
Strong HBME-1
immunoreactivity
with apical membrane
accentuation
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