Stains & molecular markers

Topic Completed: 1 June 2005

Minor changes: 25 September 2020

Copyright: 2003-2020,, Inc.

PubMed Search: HBME

Nat Pernick, M.D.
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Cite this page: Pernick N. HBME. website. Accessed October 29th, 2020.
Definition / general
  • Also called HBME-1
  • Marker of mesothelial cells, named after laboratory of Dr. Hector Battifora and MEsothelioma
  • Also positive in various thyroid carcinomas
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D.

Tumor interface

Striking membranous staining

Strong membranous HBME-1 immunoreactivity

Strong HBME-1 immunoreactivity with apical membrane accentuation

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