Stains & molecular markers
IL8


Topic Completed: 1 August 2014

Minor changes: 21 December 2020

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed Search: IL-8[title], CXCL8[title]

Nat Pernick, M.D.
Page views in 2020: 77
Page views in 2021 to date: 2
Cite this page: Pernick N. IL8. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsil8.html. Accessed January 16th, 2021.
Definition / general
  • Proinflammatory and pro-angiogenic chemokine
  • Produced by endothelial cells, epithelial cells, goblet cells (Clin Exp Allergy 2014;44:540), macrophages, mesothelial cells, smooth muscle cells in airways (Wikipedia) and various tumor cells (see below)
  • Also known as CXCL8
Pathophysiology
Clinical features
Uses by pathologists
  • No definite uses at this time
Microscopic (histologic) images

Images hosted on other servers:

Cervical cancer

Positive staining - normal
  • Endothelial cells, epithelial cells, goblet cells, macrophages, mesothelial cells, smooth muscle cells in airways
Positive staining - malignant
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