Table of Contents
Definition / general | Microscopic (histologic) images | Positive staining - normal | Positive staining - disease | Negative stainingCite this page: Pernick N. ISL1. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsisl1.html. Accessed January 16th, 2021.
Definition / general
- Insulin gene enhancer-binding protein islet-1 (ISL1); also called ISLET1, LIM homeodomain gene Islet-1 (GeneCards)
Microscopic (histologic) images
Positive staining - normal
- Cardiac stem cells (Eur J Histochem 2013;57:e14)
Positive staining - disease
- Pancreatic (well differentiated) and other neuroendocrine tumors
Negative staining
- Poorly differentiated pancreatic endocrine tumors