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Stains
ISL1
Copyright: 2015, PathologyOutlines.com, Inc.
PubMed Search: ISL1
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PubMed Search: ISL1[title]
ISL1
Author: Nat Pernick, M.D.
Topic Completed: 1 November 2013
Revised: 6 March 2019
Copyright: 2015, PathologyOutlines.com, Inc.
PubMed Search: ISL1
Sources (advertisements):
PubMed Search: ISL1[title]
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Table of Contents
Definition / general | Microscopic (histologic) images | Positive staining - normal | Positive staining - disease | Negative stainingCite this page: Pernick N. ISL1. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsisl1.html. Accessed April 6th, 2020.
Definition / general
- Insulin gene enhancer-binding protein islet-1 (ISL1); also called ISLET1, LIM homeodomain gene Islet-1 (GeneCards)
Microscopic (histologic) images
Heart between 26 and 38 days of gestation
Positive staining - normal
- Cardiac stem cells (Eur J Histochem 2013;57:e14)
Positive staining - disease
- Pancreatic (well differentiated) and other neuroendocrine tumors
Negative staining
- Poorly differentiated pancreatic endocrine tumors
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