Stains
Lambda
Copyright: 2003-2015, PathologyOutlines.com, Inc.
PubMed Search: Lambda[title]
Lambda
Author: Nat Pernick, M.D.
Topic Completed: 1 June 2005
Minor changes: 6 March 2019
Copyright: 2003-2015, PathologyOutlines.com, Inc.
PubMed Search: Lambda[title]
Cite this page: Pernick N. Lambda. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainslambda.html. Accessed May 24th, 2020.
Definition / general
- Type of immunoglobulin light chain
- Kappa/lambda ratio is usually 2:1
- Restricted expression of either kappa or lambda suggests monoclonality and a neoplastic process
Microscopic (histologic) images
Images hosted on Pathout server:
Hodgkin lymphoma: neoplastic cells have
variable cytoplasmic lambda staining, plasma
cells have intense staining and histiocytes
have weak staining
Contributed by Leica Microsystems, Biosytems division:
Myeloma of bone marrow with ISH staining for
kappa (left) and lambda (right) light chains using
Kappa Probe (PB0645), Lambda Probe (PB0669)
and Bond Polymer Refine Detection
