Stains & molecular markers
Leder stain


Topic Completed: 1 June 2005

Minor changes: 3 September 2020

Copyright: 2003-2021, PathologyOutlines.com, Inc.

PubMed Search: Leder[title] or chloroacetate esterase[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Leder stain. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsleder.html. Accessed June 23rd, 2021.
Definition / general
  • Type of enzyme histochemistry
  • Also called chloroacetate esterase
  • Chloroacetate esterase resists effects of formalin fixation and paraffin embedding
Uses by pathologists
  • Identify mast cell disorders, myeloid disorders
Positive staining - normal
  • Mast cells, myeloid cells
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