Stains & CD markers
Leder stain

Topic Completed: 1 June 2005

Minor changes: 2 July 2021

Copyright: 2003-2021,, Inc.

PubMed Search: Leder[title] or chloroacetate esterase[title]

Nat Pernick, M.D.
Page views in 2020: 1,029
Page views in 2021 to date: 761
Cite this page: Pernick N. Leder stain. website. Accessed October 15th, 2021.
Definition / general
  • Type of enzyme histochemistry
  • Also called chloroacetate esterase
  • Chloroacetate esterase resists effects of formalin fixation and paraffin embedding
Uses by pathologists
  • Identify mast cell disorders, myeloid disorders
Positive staining - normal
  • Mast cells, myeloid cells
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