Stains & CD markers
Lipochrome (lipofuscin) pigments


Topic Completed: 1 June 2005

Minor changes: 2 July 2021

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PubMed Search: Lipofuscin[title]

Nat Pernick, M.D.
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Cite this page: Pernick N. Lipochrome (lipofuscin) pigments. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainslipochrome.html. Accessed October 24th, 2021.
Definition / general
  • Breakdown products within cells from oxidation of lipids and lipoproteins
  • Also called “wear and tear” pigments in heart, liver, CNS, adrenal cortex (zona reticularis), testis interstitium and seminal vesicle
  • Stains with Sudan black B, long Ziehl-Neelson acid fast, Schmorl methods
  • Lipochrome may have strong orange autofluorescence in formalin-fixed, unstained paraffin sections
Microscopic (histologic) images

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Hepatocytes

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