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Definition / general | Positive staining - normal | Positive staining - disease | Negative stainingCite this page: Pernick N. Mesothelin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsmesothelin.html. Accessed January 22nd, 2021.
Definition / general
- 40 kDa differentiation antigen; precursor protein’s amino portion is megakaryocytic potentiating factor
- Cytoplasmic membrane glycoprotein found on surface of mesothelial cells, mesothelioma, ovarian carcinoma, pancreatic adenocarcinoma
- May place a role in cellular adhesion
Positive staining - normal
- Mesothelial cells
Positive staining - disease
- Mesothelioma, ovarian surface carcinoma
Negative staining
- Benign bile duct lesions