Stains
Mesothelin


Topic Completed: 1 June 2005

Minor changes: 28 August 2020

Copyright: 2002-2020, PathologyOutlines.com, Inc.

PubMed Search: Mesothelin [title]

Nat Pernick, M.D.
Page views in 2019: 648
Page views in 2020 to date: 793
Cite this page: Pernick N. Mesothelin. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsmesothelin.html. Accessed October 29th, 2020.
Definition / general
  • 40 kDa differentiation antigen; precursor protein’s amino portion is megakaryocytic potentiating factor
  • Cytoplasmic membrane glycoprotein found on surface of mesothelial cells, mesothelioma, ovarian carcinoma, pancreatic adenocarcinoma
  • May place a role in cellular adhesion
Positive staining - normal
  • Mesothelial cells
Positive staining - disease
  • Mesothelioma, ovarian surface carcinoma
Negative staining
  • Benign bile duct lesions
Back to top
Image 01 Image 02